Faculty Profile

News and Awards
Publications
  • Y. Gambin, V.Vandelinder, A.C.M. Ferreon, E.A. Lemke, A. Groisman, and A.A. Deniz, "Visualizing a one-way protein encounter complex by ultrafast single-molecule mixing", Nature Methods 8, (2011) PDF
  • P. Sundd, E. Gutierrez, M.K. Pospieszalska, H. Zhang, A. Groisman, and K. Ley, "Quantitative dynamic footprinting microscopy reveals mechanisms of neutrophils rolling", Nature Methods 7, 821-824,  (2010) PDF
  • E. Lemke, Y. Gambin, V. VanDelinder, E.M. Brustad, H.-W. Liu, P.G. Schultz, A. Groisman, and A. Deniz, "Microfluidic Device for  Single-Molecule Experiments with Enhanced Photostability", JACS, 13113610–13612 (2009) PDF
  • M. Polinkovsky, E. Gutierrez, A. Levchenko, and A. Groisman, "Fine temporal control of the medium gas content and acidity and on-chip generation of series of oxygen concentrations for cell cultures", Lab on a Chip9, 1073-1084 (2009) PDF
  • H.J. Cho, H. Jönsson, K. Campbell, P. Melke, J. W. Williams, B. Jedynak, A. M. Stevens, A. Groisman, and A. Levchenko, "Self-Organization in High-Density Bacterial Colonies: Efficient Crowd Control", PLoSBiology 5  (11), pp. 2614-2623 (2007)PDF
Alexander Groisman

Alexander Groisman

Ph. D., Weizman Inst. of Science, Israel, 2000

Contact

Web: Homepage
Office: UH 7254
Phone: 858-822-1838

Research Statement

- Biolistic delivery and gene guns

- Kinetics and thermodynamics of protein folding

- Imaging of the development and behavior of C. elegans worms

- Imaging of primary and cultured leukocytes for HIV studies

- Microbial cultures in microchambers

- Chemotaxis, chemotropism, aerotaxis, thermotaxis and gradient response of cells and organisms

- Perfusion chambers to study the rolling, adhesion, and migration of blood cells and unicellular organisms

- Substrate rigidity sensing, traction force and TIRF microscopy of mammalian cells

- Oxygen level control and hypoxia on the cell and organism levels